Past Clinical Research Studies 

Below is a complete list of past ARC Clinical Research studies. Please submit a request online if you need further information about these past studies or how to participate. 


  • Adult COVID-19 Vaccine Study

    • A two-part research study that examined the safety and efficacy of investigational vaccine booster regimens to prevent COVID-19 (including the delta variant).
  • Ankylosing Spondylitis Study

    • The ankylosing spondylitis study was a 16-week study with visits 2 to 4 weeks apart that enrolled patients 18 to 65 years of age.
  • Arthritis Studies Study

    • Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee

    Sponsor: Pfizer   Sponsor Link

  •  Atopic Dermatitis Study

    • A study for patients with moderate to severe atopic dermatitis (or eczema). There are more than 3 million cases per year in the US and some may see no relief from topical treatments alone. Symptoms may include inflamed, rough, itchy, or cracked skin. This issue can further lead into complications like skin infections and sleep issues. We are happy to provide this clinical research option to our patients and serve as an ancillary service at Austin Regional Clinic.


  •  C-Diffense Study 

    • Vaccine study aimed to prevent clostridium difficile, or C. diff, infections. The study is enrolling people over age 50 who are at high risk of catching C. diff, but have no prior history of C. diff infection.


  • C-Diffense Vaccine Study

    • Diff Vaccination study, participants will be randomly assigned in parallel in a 1:1 ratio to receive C difficile vaccine (200µg total toxoid) at months 0, 1, and 6 (3-dose group) or at months 0 and 6 (2-dose group). The participants in the 2-dose group will receive placebo (saline) at Month 1.


  • Colonoscopy Study

    • The purpose of this study was to collect stool and blood samples to develop a test for screening for colorectal cancer screening.


  • COVID-19 Janssen Vaccine Study

    • Austin Regional Clinic is looking for volunteers from diverse backgrounds to research an investigational vaccine.

    Sponsor: Janssen

  • COVID-19 Pfizer Vaccine Study

    • ARC Clinical Research COVID-19 study with Pfizer COVID vaccine teen study evaluating the vaccine among the 12 - 17 year olds. 

    Sponsor: Pfizer 

  • COVID-19 Treatment Study

    • ARC Clinical Research COVID-19 study to help people who were showing symptoms of COVID-19 or had been in close contact with someone who has COVID-19.
  • COVID-19 Vaccine Pediatric Study

    • ARC Clinical Research study to learn if the COVID-19 study vaccine can produce an immune response against COVID-19, and if it is safe, in children 12 to 15 years old.
  •  Discovering New Biomarkers Assays for CRC Detection



  • Endocrinology (Diabetes, Lipids)

    • Safety and Efficacy Study of Sotagliflozin on Glucose Control in Patients With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control (SOTA-CKD3)

    Sponsor: Sanofi

    Sponsor Link


    • A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe Hypertriglyceridemia (INDIGO-1)

    Sponsor: Gemphire Therapeutics, Inc.

    Sponsor Link


    • Gan & Lee Insulin Glargine Target Type (2) Evaluating Research (GLITTER 2)

    Sponsor: Gan and Lee Pharmaceuticals

    Sponsor Link


    • Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

    Sponsor: The Medicines Company

    Sponsor Link

  • Endometriosis and Uterine Fibroids

    • This study was looking for women aged 18-49 who are diagnosed with endometriosis and experiencing moderate to severe pain associated to their endometriosis.


  • Fibromyalgia Device

    • This study was for an investigational smart phone app, intended to reduce fibromyalgia symptoms and help people manage their fibromyalgia more effectively. It did not involve any drugs or medications.


  • Gastroenterology

    • Study of a Candidate Clostridium Difficile Toxoid Vaccine in Subjects at Risk for C. Difficile Infection

    Sponsor: Sanofi Pasteur

    Sponser Link

  •  Gynecology (Women’s Health)

    • Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids (PRIMROSE 1)

    Sponsor: ObsEva SA

    Sponsor Link

  • Healthy Volunteers

    • A Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Otherwise Healthy Patients With Influenza (CAPSTONE 1)

    Sponsor: Shionogi  Sponsor Link


    • Study of S-033188 (Baloxavir Marboxil) Compared With Placebo or Oseltamivir in Patients With Influenza at High Risk of Influenza Complications (CAPSTONE 2) 

    Sponsor: Shionogi Sponsor Link


    • Point-of-Care Immunoassay for Detection of Bacterial Sinusitis

    Sponsor: ENTvantage Dx Sponsor Link


    • An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now

    Sponsor: Exact Sciences Corporation Sponsor Link

  •  Herediatary Angioedema (HAE)

    • Hereditary angioedema (HAE) is caused by a low-level or improper function of a protein called the C1 inhibitor. With HAE, the blood vessels are affected. An HAE attack can result in rapid swelling of the hands, feet, limbs, face, intestinal tract, larynx (voice box), or trachea (windpipe)
  •  Hot Flash

    • This study was a research trial for a medication to help postmenopausal women suffering from hot flashes.
  •  Inflammatory Disease

    • This study is for patients who may have been diagnosed with lupus.
  •  Melanoma

    • A biomarker is an indicator that can be found in blood, stool, urine or other bodily fluids and tissues that may show certain diseases. If accurate, biomarkers can be found for diseases, such as cancer, and could lead to earlier and less invasive discovery. The purpose of this opportunity is to study blood samples to detect biomarkers that could be used to improve melanoma detection. 
  •  Melanoma Blood Sample Collection

    • The primary objective of this study is to obtain de-identified, clinically characterized, whole blood specimens from subjects with untreated melanoma to evaluate biomarkers associated with cancer as potential targets for diagnostic assays and to support subsequent assay development activities.


  •  Pediatric ASD Diagnosis

    • Autism Spectrum Disorder (ASD) is a developmental disorder that affects communication and behavior. As of now there is a guide created by the American Psychiatric Association to help health care professionals diagnose ASD. This test is performed in a secondary care setting and can take several hours to administrate. However, it can still be difficult to diagnose since there’s no defined test such as a blood test.


  •  Pediatric Meningococcal Vaccine

    • The pediatric meningococcal vaccine study explored the effectiveness of a vaccine for infants between the ages of ≥ 42 to ≤ 89 days.


  • Psoriatic Arthritis

    • The psoriatic arthritis study is a 48-week biologic naïve study with a possible long-term extension. Visits are every 4 weeks.
  • Psoriatic Arthritis With Back Pain

    • The biologic naïve psoriatic arthritis with axial disease study is a 60-week study with visits every 4 weeks. Patients must be 18 years or older with no more than 1 non-biologic medication: active plaque psoriasis or history of psoriasis.
  • Pulmonology (Asthma)

    • Observational Study of Obstructive Lung Disease (NOVELTY) (NOVELTY)

    Sponsor: AstraZeneca

    Sponsor Link


    • A Phase III Parallel Group Study, Comparing the Efficacy, Safety and Tolerability of the Fixed Dose Combination (FDC) of Fluticasone Furoate+Umeclidinium Bromide+Vilanterol (FF/UMEC/VI) With the FDC of FF/VI in Subjects With Inadequately Controlled Asthma

    Sponsor: GlaxoSmithKline

    Sponsor Link


    • A BE Study to Compare Beclomethasone Dipropionate Inhalation Aerosol, 40 mcg and QVAR® 40 mcg, Inhalation Aerosol

    Sponsor: Amneal Ireland Limited

    Sponsor Link

  • Oncology (Cancer)

    • Blood Sample Collection to Evaluate Biomarkers for Hepatocellular Carcinoma

    Sponsor: Exact Sciences Corporation

    Sponsor Link

  • Rapid Bacterial Sinusitis Testing

    • ARC clinical study for patients who had sinusitis diagnosis but otherwise healthy.
  • Sjogren’s Syndrome

    • The Sjogren’s syndrome study is a 36-week study looking for patients with primary Sjogren's disease diagnosis, age 18 to 75 inclusive.
  • Stroke Detection Device

    • Austin Regional Clinic is doing a study to learn if there are better ways to identify irregular heartbeats and protect older adults from stroke.
  • Subacute Cutaneous Lupus Erythematosus (SCLE) and Discoid Lupus Erythematosus (DLE)

    • The Subacute Cutaneous Lupus (SCLE) and Discoid Lupus Erythematosus (DLE) study is a 33-week study for patients 18 to 75 years of age with more than 6 months of documented medical history of cutaneous lupus or discoid lupus, confirmed with either a biopsy or photography.
  • Systemic Lupus Erythematosus

    • The systemic lupus erythematosus clinical study is a 52-week study looking for patients 18 to 75 years of age, taking at least one but not more than two non-biologic medications.
  • Vagus Nerve Stimulator Device

    • The adult vagus nerve stimulator device study evaluated the vagus nerve stimulator for the treatment of rheumatoid arthritis. The first 12 weeks were the primary study which, upon completion, participants may have continued for the long-term phase.